CAGLIARI, ITALY – SEPTEMBER 27: Lautaro Martinez of Inter celebrates scoring the opening goal during the Serie A match between Cagliari Calcio and FC Internazionale at Stadio Sant’Elia on September 27, 2025 in Cagliari, Italy. (Photo by Enrico Locci/Getty Images)
Inter pick Francesco Pio Esposito to partner Lautaro Martinez upfront, with Davide Frattesi and Piotr Zielinski in midfield for the Champions League with giant-killers Union Saint-Gilloise.
It kicks off at the RSC Anderlecht Stadium at 20.00 UK time (19.00 GMT).

The Nerazzurri had a stuttering start to the season, but have really found their feet under new coach Cristian Chivu, notching up six consecutive victories in all competition.
That includes both Champions League fixtures, sweeping Ajax aside 2-0 in Amsterdam and Slavia Praha 3-0 at San Siro.
Now they are in Belgium with Marcus Thuram, Matteo Darmian and Raffaele Di Gennaro still on the treatment table.
While Ange-Yoan Bonny scored the winner against Roma on Saturday, it is Italy international Pio Esposito who partners Lautaro Martinez here.
There is squad rotation with the introduction of Yann Bisseck, Stefan de Vrij, Frattesi, Zielinski and Carlos Augusto too.

Belgians Union Saint-Gilloise were surprise qualifiers for their first ever Champions League tournament, but have already made their mark as giant-killers with a surprise 3-1 win away to PSV Eindhoven.
However, they then lost 4-0 at home to Newcastle United.
Coach Sebastien Pocognoli was poached by AS Monaco, so David Hubert made his debut at the weekend with a 3-1 win over Charleroi.
The hosts are missing injured Mohammed Fuseini, while Guillaume Francois, Jens Teunckens and Ivan Pavlic are not on the Champions League list.
Canada international Promise David leads the attack with support from Anouar Ait El Hadj rather than Raul Florucz.
Defender Kevin Mac Allister is the brother of Liverpool star Alexis.
Union Saint-Gilloise vs. Inter line-ups
Union Saint-Gilloise: Scherpen; Mac Allister, Burgess, Leysen; Khalaili, Zorgane, Rasmussen, Van de Perre, Niang; Ait El Hadj, David
Union SG bench: Chambaere, Barry, Guilherme Smith, Rodriguez, Schoofs, Giger, Boufal, Sykes, Patris, Florucz
Inter: Sommer; Bisseck, De Vrij, Bastoni; Dumfries, Frattesi, Calhanoglu, Zielinski, Carlos Augusto; Lautaro Martinez, Esposito
Inter bench: J Martinez, Calligaris, Sucic, Luis Henrique, Bonny, Acerbi, Diouf, Mkhitaryan, Barella, Akanji, Dimarco
Ref: Nyberg (SWE)
Source From: Football Italia
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